By Gustavo Maroni
Drosophila, the typical fruit fly, is the main commonly studied of all organisms from the perspective of genetics and cytology. This atlas summarizes what's identified in regards to the nearly a hundred Drosophila genes for which the full nucleotide series is understood. every one access features a description of the gene's molecular association and expression, the whole nucleotide and amino acid sequences, maps of attention-grabbing buildings, highlights of practical positive aspects and promoter regulatory areas, and chosen references to the first literature. A separate component to the atlas considers various facets of gene association as they take place within the Drosophila genome. subject matters lined comprise measurement correlations between a number of genetic components, splicing signs, translation initiation signs, and codon bias. The paintings represents a brand new milestone in summarizing present details and making it simply obtainable to geneticists and biologists.
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Extra info for An Atlas of Drosophila Genes: Sequences and Molecular Features
Biol. 10:206-216. -T. and Keller, E. B. (1990b). Positive and negative regulatory elements mediating transcription from the Drosophila melanogaster Actin 5C distal promoter. Mol. Cell. Biol. 10:6172-6180. Couderc, J. , Sobrier, M. L. and Dastugue, B. (1987). 20-Hydroxyecdysone regulates cytoplasmic actin gene expression in Drosophila cultured cells. Nucleic Acid Res. 15:2549-2561. Courchesne-Smith, C. L. and Tobin, S. L. (1989). Tissue-specific expression of the 79B actin gene during Drosophila development.
J. (1983). Two 36 AN ATLAS OF DROSOPHILA GENES Drosophila actin genes in detail. Gene structure, protein structure and transcription during development. J. Mol. Biol. 163:533-551. , Hennessey, E. and White, D. (1991). Protein engineering and the study of muscle contraction in Drosophila flight muscles. J. Cell. Sci. Suppl. 14:73-78. Tobin, S. , Cook, P. J. and Burn, T. C. (1990). Transcriptions of individual Drosophila actin genes are differentially distributed during embryogenesis. Dev. Genet.
Act79B Gene Organization and Expression The 5' end was determined by S1 mapping. The 3' end has not been determined. There is an intron within the Gly-309 codon (Act79B Sequence) (Fyrberg et al. 1981; Sanchez et al. 1983). Developmental Pattern Transcription is undetectable in embryos (Tobin et al. 1990), it increases during the first larval instar, peaks during the second instar and diminishes in the third instar and in prepupae. Another small burst of transcription occurs during pupation (Sanchez et al.